Phellodendron Amurense Bark Extract for Skin Berberine-Rich Botanical for Skin Barrier & Inflammatory Support
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Derived from the dried bark of Phellodendron amurenseRupr. (Amur Cork Tree), this standardized extract is a cornerstone of Traditional Chinese Medicine (TCM) with modern dermatological validation. Known for its high berberine content, it delivers targeted support for skin barrier integrity, inflammatory modulation, and microbial balance—ideal for topical and nutraceutical applications.
- Loss on Drying ≤5.0% | Heavy Metals: NMT 10ppm (Pb, As, Cd, Hg)
- Particle Size: 100% through 80-mesh sieve
- Total Plate Count ≤1,000 CFU/g | Yeast/Mold ≤100 CFU/g
- Pathogens: Non-detectable E. coli, Salmonella, Staphylococcus aureus
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Anti-Inflammatory & Barrier Support
Berberine inhibits NF-κB signaling and reduces pro-inflammatory cytokines (IL-6, TNF-α), alleviating redness and irritation. Preclinical studies show enhanced skin barrier function via ceramide synthesis promotion.
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Antimicrobial & Antifungal Action
In vitro data confirms inhibitory effects against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and dermatophytes (Trichophyton mentagrophytes, Microsporum canis).
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Acne & Sebum Regulation
Modulates sebaceous gland activity and suppresses Cutibacterium acnesproliferation, aligning with traditional use for "damp-heat" skin conditions (e.g., acne, oily skin).
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Wound Healing Acceleration
Upregulates growth factors (EGF, TGF-β) and collagen deposition in preclinical models, supporting epidermal repair for minor cuts or post-procedure recovery.
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Cosmeceuticals:
Key ingredient in anti-inflammatory creams, acne treatments, and post-sun repair serums (compatible with aqueous/alcohol-based formulations).
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Nutraceuticals:
Oral supplement for systemic skin wellness (e.g., eczema, psoriasis adjunctive support).
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Pharmaceuticals:
Excipient for topical antimicrobial ointments and dermatological drug delivery systems.
- GMP-certified production with full bark-to-extract traceability
- Custom berberine concentrations (90%-99%) and solubility optimization (aqueous/ethanol-soluble options)
- Compliance with USP <561> (Botanical Extracts) and ISO 22000 standards
- Stability-validated packaging (25kg/drum) for global logistics